TY - JOUR
T1 - Sesquiterpene polyol esters from the leaves of Maytenus macrocarpa
AU - Chávez, H.
AU - Callo, N.
AU - Estévez-Braun, A.
AU - Ravelo, A. G.
AU - González, A. G.
PY - 1999/11
Y1 - 1999/11
N2 - The aerial parts of Maytenus macrocarpa yielded three new β- dihydroagarofuran sesquiterpene polyol esters. Their structures were elucidated by spectroscopic analyses including 2D NMR techniques as 6β,8β,15-triacetoxy-1α,9α-dibenzoyloxy-4β-hydroxy-β-dihydroagarofuran (1); 1α,6β,8β,15-tetraacetoxy-9α-benzoyloxy-4β-hydroxy-β- dihydroagarofuran (2) and (1S,4S,6R,7R,8R,9R)-1,6,15-triacetoxy-8,9- dibenzoyloxy-4-hydroxy-β-dihydroagarofuran (3). Compounds 1 and 2 showed marginal antitumor activity against four cell lines.
AB - The aerial parts of Maytenus macrocarpa yielded three new β- dihydroagarofuran sesquiterpene polyol esters. Their structures were elucidated by spectroscopic analyses including 2D NMR techniques as 6β,8β,15-triacetoxy-1α,9α-dibenzoyloxy-4β-hydroxy-β-dihydroagarofuran (1); 1α,6β,8β,15-tetraacetoxy-9α-benzoyloxy-4β-hydroxy-β- dihydroagarofuran (2) and (1S,4S,6R,7R,8R,9R)-1,6,15-triacetoxy-8,9- dibenzoyloxy-4-hydroxy-β-dihydroagarofuran (3). Compounds 1 and 2 showed marginal antitumor activity against four cell lines.
UR - http://www.scopus.com/inward/record.url?scp=0345072548&partnerID=8YFLogxK
U2 - 10.1021/np990232f
DO - 10.1021/np990232f
M3 - Artículo
AN - SCOPUS:0345072548
SN - 0163-3864
VL - 62
SP - 1576
EP - 1577
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 11
ER -