Resultados del uso de la fibrina rica en plaquetas y rellenos óseos en la regeneración ósea guiada. Revisión sistemática

Miguel Ángel Núñez Muñoz, Yuri Castro-Rodríguez

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva


Objective: To evaluate systematically the results obtained by combining platelet rich fibrin (PRF) and bone fill in guided bone regeneration, according to scientific literature. Materials and method: Detailed search of database from PubMed, Scopus, Web of Science, ScienceDirect, Cochrane and SciELO to obtain the most updated information of clinical results (bone filling degree, surgical success, implant mobility, post-surgical complications, and implant survival) of the cases treated with PRF and the cases where the platelet rich fibrin was combined with a bone filler. Those results registered and compared. Results: From the 965 files initially identified, were excluded clinical reports, reviews, observational studies, comments, studies with pediatric patients and so on. There were included 12 clinical essays where the variables of the technique with PRF and the technique where the PRF was combined with a bone filler were contrasted. Conclusion: The combination of PRF plus bone filler promotes bone neoformation, increased trabecular bones, and improved healing times; however, after 6 months of monitoring, the results were not significantly different with the groups that did not use the PRF in the procedure of maxillary sinus floor lift with lateral window technique. Regarding the preservation of alveolar ridge the different studies are not conclusive: some indicate that the mixture of a concentrate with a bone filling seems to improve the volumetric proportions; however, other studies report bone loss in width and even greater degree of inflammation.

Título traducido de la contribuciónResults of platelet rich fibrin and bone grafts in guided bone regeneration. A systematic review
Idioma originalEspañol
Páginas (desde-hasta)126-137
Número de páginas12
PublicaciónRevista Espanola de Cirugia Oral y Maxilofacial
EstadoPublicada - 2019
Publicado de forma externa

Nota bibliográfica

Publisher Copyright:
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Palabras clave

  • Alveolar ridge augmentation
  • Bone regeneration
  • Bone transplantation
  • Fibrin
  • Loss of alveolar bone
  • Maxillary sinus
  • Plasma rich in platelets


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