Friedelane triterpenoids from Maytenus macrocarpa

H. Chavez, A. Estevez-Braun, A. G. Ravelo, A. G. Gonzalez

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

36 Citas (Scopus)


A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa. It includes a new friedelan triterpene (1), together with the known compounds friedelin, 3-oxo-29-hydroxyfriedelane, 3- oxofriedelan-25-al, and canophyllol. The structures of these compounds were elucidated by spectroscopic and chemical evidence. Complete 1H and 13C assignments were achieved by 2D NMR spectroscopy. The new compound showed weak activity against aldose reductase. It did not display antitumor activity against P-388 lymphoid neoplasm, A-549 human lung carcinoma, HT-29 human colon carcinoma, or MEL-28 human melanoma cell lines.

Idioma originalInglés
Páginas (desde-hasta)82-85
Número de páginas4
PublicaciónJournal of Natural Products
EstadoPublicada - 1998
Publicado de forma externa


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