Cytotoxic triterpenoids from Maytenus retusa

Sandra M. Oramas-Royo; Haydee Chávez; Patricia Martín-Rodríguez; Leandro Fernández-Pérez; Ángel G. Ravelo; Ana Estévez-Braun

doi:10.1021/np100517u

Cytotoxic triterpenoids from Maytenus retusa

Sandra M. Oramas-Royo
, Haydee Chávez
, Patricia Martín-Rodríguez
, Leandro Fernández-Pérez
, Ángel G. Ravelo
, Ana Estévez-Braun

Instituto Universitario de Bio-Orgánica 'Antonio González'
Universidad Nacional "San Luis Gonzaga" de Ica
University of Las Palmas de Gran Canaria

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

31 Citas (Scopus)

Resumen

Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by 1D and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC₅₀ values ranging between 0.2 and 4.7 μM.

Idioma original	Inglés
Páginas (desde-hasta)	2029-2034
Número de páginas	6
Publicación	Journal of Natural Products
Volumen	73
N.º	12
DOI	https://doi.org/10.1021/np100517u
Estado	Publicada - 27 dic. 2010

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abstract = "Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by 1D and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC50 values ranging between 0.2 and 4.7 μM.",

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AU - Oramas-Royo, Sandra M.

AU - Chávez, Haydee

AU - Martín-Rodríguez, Patricia

AU - Fernández-Pérez, Leandro

AU - Ravelo, Ángel G.

AU - Estévez-Braun, Ana

PY - 2010/12/27

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AB - Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by 1D and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC50 values ranging between 0.2 and 4.7 μM.

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Cytotoxic triterpenoids from Maytenus retusa

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