Cytotoxic triterpenoids from Maytenus retusa

Sandra M. Oramas-Royo, Haydee Chávez, Patricia Martín-Rodríguez, Leandro Fernández-Pérez, Ángel G. Ravelo, Ana Estévez-Braun

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

24 Citas (Scopus)

Resumen

Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by 1D and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC50 values ranging between 0.2 and 4.7 μM.

Idioma originalInglés
Páginas (desde-hasta)2029-2034
Número de páginas6
PublicaciónJournal of Natural Products
Volumen73
N.º12
DOI
EstadoPublicada - 27 dic. 2010

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