TY - JOUR
T1 - Cytotoxic triterpenoids from Maytenus retusa
AU - Oramas-Royo, Sandra M.
AU - Chávez, Haydee
AU - Martín-Rodríguez, Patricia
AU - Fernández-Pérez, Leandro
AU - Ravelo, Ángel G.
AU - Estévez-Braun, Ana
PY - 2010/12/27
Y1 - 2010/12/27
N2 - Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by 1D and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC50 values ranging between 0.2 and 4.7 μM.
AB - Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by 1D and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC50 values ranging between 0.2 and 4.7 μM.
UR - http://www.scopus.com/inward/record.url?scp=78650743876&partnerID=8YFLogxK
U2 - 10.1021/np100517u
DO - 10.1021/np100517u
M3 - Artículo
C2 - 21090801
AN - SCOPUS:78650743876
SN - 0163-3864
VL - 73
SP - 2029
EP - 2034
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 12
ER -