Cheiloclines A-I. First examples of octacyclic sesquiterpene-triterpene hetero-Diels-Alder adducts

Dulce Mesa-Siverio; Haydee Chávez; Ana Estévez-Braun; Ángel G. Ravelo

doi:10.1016/j.tet.2004.10.074

Cheiloclines A-I. First examples of octacyclic sesquiterpene-triterpene hetero-Diels-Alder adducts

Dulce Mesa-Siverio
, Haydee Chávez
, Ana Estévez-Braun
, Ángel G. Ravelo

University of La Laguna
Hospital Universitario Nuestra Senora de Candelaria

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

16 Citas (Scopus)

Resumen

Cheiloclines A-I (1-9) have been isolated from the root bark of Cheiloclinium hippocratioides (Celastraceae). They represent the first examples of hetero-Diels-Alder adducts between a nor-triterpenequinone and a sesquiterpene. Their structures were elucidated on the basis of spectral analysis, including homonuclear and heteronuclear correlation NMR experiments (COSY, ROESY, HSQC and HMBC). These compounds were tested for antitumoral, antibacterial and aldose reductase inhibitory activities.

Idioma original	Inglés
Páginas (desde-hasta)	429-436
Número de páginas	8
Publicación	Tetrahedron
Volumen	61
N.º	2
DOI	https://doi.org/10.1016/j.tet.2004.10.074
Estado	Publicada - 10 ene. 2005

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abstract = "Cheiloclines A-I (1-9) have been isolated from the root bark of Cheiloclinium hippocratioides (Celastraceae). They represent the first examples of hetero-Diels-Alder adducts between a nor-triterpenequinone and a sesquiterpene. Their structures were elucidated on the basis of spectral analysis, including homonuclear and heteronuclear correlation NMR experiments (COSY, ROESY, HSQC and HMBC). These compounds were tested for antitumoral, antibacterial and aldose reductase inhibitory activities.",

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AU - Mesa-Siverio, Dulce

AU - Chávez, Haydee

AU - Estévez-Braun, Ana

AU - Ravelo, Ángel G.

PY - 2005/1/10

Y1 - 2005/1/10

N2 - Cheiloclines A-I (1-9) have been isolated from the root bark of Cheiloclinium hippocratioides (Celastraceae). They represent the first examples of hetero-Diels-Alder adducts between a nor-triterpenequinone and a sesquiterpene. Their structures were elucidated on the basis of spectral analysis, including homonuclear and heteronuclear correlation NMR experiments (COSY, ROESY, HSQC and HMBC). These compounds were tested for antitumoral, antibacterial and aldose reductase inhibitory activities.

AB - Cheiloclines A-I (1-9) have been isolated from the root bark of Cheiloclinium hippocratioides (Celastraceae). They represent the first examples of hetero-Diels-Alder adducts between a nor-triterpenequinone and a sesquiterpene. Their structures were elucidated on the basis of spectral analysis, including homonuclear and heteronuclear correlation NMR experiments (COSY, ROESY, HSQC and HMBC). These compounds were tested for antitumoral, antibacterial and aldose reductase inhibitory activities.

KW - Diels-Alder reaction

KW - Metabolites

KW - NMR

KW - Plants

KW - Terpenoids

UR - https://www.scopus.com/pages/publications/9744273201

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DO - 10.1016/j.tet.2004.10.074

M3 - Artículo

AN - SCOPUS:9744273201

SN - 0040-4020

VL - 61

SP - 429

EP - 436

JO - Tetrahedron

JF - Tetrahedron

IS - 2

ER -

Cheiloclines A-I. First examples of octacyclic sesquiterpene-triterpene hetero-Diels-Alder adducts

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