Cheiloclines A-I. First examples of octacyclic sesquiterpene-triterpene hetero-Diels-Alder adducts

Dulce Mesa-Siverio, Haydee Chávez, Ana Estévez-Braun, Ángel G. Ravelo

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

15 Citas (Scopus)

Resumen

Cheiloclines A-I (1-9) have been isolated from the root bark of Cheiloclinium hippocratioides (Celastraceae). They represent the first examples of hetero-Diels-Alder adducts between a nor-triterpenequinone and a sesquiterpene. Their structures were elucidated on the basis of spectral analysis, including homonuclear and heteronuclear correlation NMR experiments (COSY, ROESY, HSQC and HMBC). These compounds were tested for antitumoral, antibacterial and aldose reductase inhibitory activities.

Idioma originalInglés
Páginas (desde-hasta)429-436
Número de páginas8
PublicaciónTetrahedron
Volumen61
N.º2
DOI
EstadoPublicada - 10 ene. 2005

Nota bibliográfica

Funding Information:
This work has been funded by the Spanish MCYT (SAF2003-04200-C02-02) and by the ICIC (Instituto Canario de Investigación del Cáncer). D.M.S. thanks Caja Canarias-ULL for a predoctoral fellowship.

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