An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation

Sandra Jiménez-Alonso; Haydee Chávez; Ana Estévez-Braun; Ángel G. Ravelo; Gabriela Feresin; Alejandro Tapia

doi:10.1016/j.tet.2008.06.057

An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation

Sandra Jiménez-Alonso, Haydee Chávez, Ana Estévez-Braun, Ángel G. Ravelo, Gabriela Feresin, Alejandro Tapia

FARMACIA Y BIOQUIMICA

Resultado de la investigación: Contribución a una revista › Artículo › revisión exhaustiva

11 Citas (Scopus)

Resumen

The synthesis of novel pyrano embelin derivatives has been achieved through domino Knoevenagel hetero Diels-Alder reactions of embelin (1) with paraformaldehyde and electron rich alkenes. This synthetic approach is highly efficient when microwave irradiation is used.

Idioma original	Inglés
Páginas (desde-hasta)	8938-8942
Número de páginas	5
Publicación	Tetrahedron
Volumen	64
N.º	37
DOI	https://doi.org/10.1016/j.tet.2008.06.057
Estado	Publicada - 8 set. 2008

Nota bibliográfica

Funding Information:
This work has been funded by the Spanish MCYT (SAF2006-06720) and by ICIC. S.J.-A. thanks the MCYT for a predoctoral fellowship. We thank Dr. García-Tellado for granting access to the microwave apparatus.

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10.1016/j.tet.2008.06.057

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@article{39121fe54023483dad0415795396da28,

title = "An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation",

abstract = "The synthesis of novel pyrano embelin derivatives has been achieved through domino Knoevenagel hetero Diels-Alder reactions of embelin (1) with paraformaldehyde and electron rich alkenes. This synthetic approach is highly efficient when microwave irradiation is used.",

keywords = "Knoevenagel heteroDiels-Alderreactions, Multicomponent reactions, MW irradiation, Quinones",

author = "Sandra Jim{\'e}nez-Alonso and Haydee Ch{\'a}vez and Ana Est{\'e}vez-Braun and Ravelo, {{\'A}ngel G.} and Gabriela Feresin and Alejandro Tapia",

note = "Funding Information: This work has been funded by the Spanish MCYT (SAF2006-06720) and by ICIC. S.J.-A. thanks the MCYT for a predoctoral fellowship. We thank Dr. Garc{\'i}a-Tellado for granting access to the microwave apparatus. ",

year = "2008",

month = sep,

day = "8",

doi = "10.1016/j.tet.2008.06.057",

language = "Ingl{\'e}s",

volume = "64",

pages = "8938--8942",

journal = "Tetrahedron",

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T1 - An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation

AU - Jiménez-Alonso, Sandra

AU - Chávez, Haydee

AU - Estévez-Braun, Ana

AU - Ravelo, Ángel G.

AU - Feresin, Gabriela

AU - Tapia, Alejandro

N1 - Funding Information: This work has been funded by the Spanish MCYT (SAF2006-06720) and by ICIC. S.J.-A. thanks the MCYT for a predoctoral fellowship. We thank Dr. García-Tellado for granting access to the microwave apparatus.

PY - 2008/9/8

Y1 - 2008/9/8

N2 - The synthesis of novel pyrano embelin derivatives has been achieved through domino Knoevenagel hetero Diels-Alder reactions of embelin (1) with paraformaldehyde and electron rich alkenes. This synthetic approach is highly efficient when microwave irradiation is used.

AB - The synthesis of novel pyrano embelin derivatives has been achieved through domino Knoevenagel hetero Diels-Alder reactions of embelin (1) with paraformaldehyde and electron rich alkenes. This synthetic approach is highly efficient when microwave irradiation is used.

KW - Knoevenagel heteroDiels-Alderreactions

KW - Multicomponent reactions

KW - MW irradiation

KW - Quinones

UR - http://www.scopus.com/inward/record.url?scp=48049104329&partnerID=8YFLogxK

U2 - 10.1016/j.tet.2008.06.057

DO - 10.1016/j.tet.2008.06.057

M3 - Artículo

AN - SCOPUS:48049104329

SN - 0040-4020

VL - 64

SP - 8938

EP - 8942

JO - Tetrahedron

JF - Tetrahedron

IS - 37

ER -

An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation

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