Understanding the Global Transmission and Demographic Distribution of Nipah Virus (NiV)

Md Rezwan Ahmed Mahedi, Anurag Rawat, Fazle Rabbi, K. Suresh Babu, Elias Salvador Tasayco, Franklin Ore Areche, Olga Vicentina Pacovilca-Alejo, Denis Dante Corilla Flores, Salomón Vivanco Aguilar, Fredmoore L. Orosco, Nikolaos Syrmos, Mustafa Mudhafar, Sadia Afrin, Mst Mahfuza Rahman

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Nipah virus (NIV) infection was identified in 1998, in Malaysia. The virus belongs to the Paramyxoviridae family. In the past, the virus was spread in Bangladesh, India, as well as Singapore. It affects our nervous system and the respiratory system, which is highly dangerous for our lives. It is caused by an RNA virus and has a high mortality rate. This virus can be transmitted from bats to humans, pigs to humans, or humans to humans. It is conceptualized that fruit bats like Pteropus vampyrus and Pteropus hypomelanus are responsible for transmitting the virus. From 1999 to 2022, there is no approved vaccine and medicines for the treatment of nipah virus infection. The fatality rate of this nipah virus is 75% to 95%. Moreover, NiV B (Bangladesh) is more deathly than NiV M (Malaysia). In present, some vaccines are under trial on pigs, horses and the monkey. In this review we try to focus on the barrier of vaccine and medicine development for this nipah virus.

Original languageEnglish
Pages (from-to)3588-3594
Number of pages7
JournalResearch Journal of Pharmacy and Technology
Volume16
Issue number8
DOIs
StatePublished - Aug 2023

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Keywords

  • Bangladesh, etc
  • Bats
  • Encephalitis
  • Molecular Epidemiology
  • Nipah virus (NIV)
  • Pathogenicity
  • Respiratory system

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