Sesquiterpene polyol esters from the leaves of Maytenus macrocarpa

H. Chávez, N. Callo, A. Estévez-Braun, A. G. Ravelo, A. G. González

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

The aerial parts of Maytenus macrocarpa yielded three new β- dihydroagarofuran sesquiterpene polyol esters. Their structures were elucidated by spectroscopic analyses including 2D NMR techniques as 6β,8β,15-triacetoxy-1α,9α-dibenzoyloxy-4β-hydroxy-β-dihydroagarofuran (1); 1α,6β,8β,15-tetraacetoxy-9α-benzoyloxy-4β-hydroxy-β- dihydroagarofuran (2) and (1S,4S,6R,7R,8R,9R)-1,6,15-triacetoxy-8,9- dibenzoyloxy-4-hydroxy-β-dihydroagarofuran (3). Compounds 1 and 2 showed marginal antitumor activity against four cell lines.

Original languageEnglish
Pages (from-to)1576-1577
Number of pages2
JournalJournal of Natural Products
Volume62
Issue number11
DOIs
StatePublished - Nov 1999
Externally publishedYes

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