TY - JOUR
T1 - Recent studies on natural products as anticancer agents
AU - Ravelo, Ángel G.
AU - Estévez-Braun, Ana
AU - Chávez-Orellana, Haydee
AU - Pérez-Sacau, Elisa
AU - Mesa-Siverio, Dulce
PY - 2004
Y1 - 2004
N2 - Cancer will be the major cause of death in the 21st century and natural products should provide novel and more effective anticancer agents. This review deals with new natural molecules liable to become anticancer drugs, as well as recent specific strategies for a selective treatment of cancer. The introduction presents the current state of the art on anticancer research. Beside, in the following subheadings we summarize our research on cytotoxic natural quinone methide-triperpenes and their analogues. We also discuss our results on the anti-tumour promoting activity of natural naphthoquinones and their derivatives.
AB - Cancer will be the major cause of death in the 21st century and natural products should provide novel and more effective anticancer agents. This review deals with new natural molecules liable to become anticancer drugs, as well as recent specific strategies for a selective treatment of cancer. The introduction presents the current state of the art on anticancer research. Beside, in the following subheadings we summarize our research on cytotoxic natural quinone methide-triperpenes and their analogues. We also discuss our results on the anti-tumour promoting activity of natural naphthoquinones and their derivatives.
UR - http://www.scopus.com/inward/record.url?scp=3042518847&partnerID=8YFLogxK
U2 - 10.2174/1568026043451500
DO - 10.2174/1568026043451500
M3 - Artículo de revisión
C2 - 14754457
AN - SCOPUS:3042518847
SN - 1568-0266
VL - 4
SP - 241
EP - 265
JO - Current Topics in Medicinal Chemistry
JF - Current Topics in Medicinal Chemistry
IS - 2
ER -
