Friedelane triterpenoids from Maytenus macrocarpa

H. Chavez, A. Estevez-Braun, A. G. Ravelo, A. G. Gonzalez

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa. It includes a new friedelan triterpene (1), together with the known compounds friedelin, 3-oxo-29-hydroxyfriedelane, 3- oxofriedelan-25-al, and canophyllol. The structures of these compounds were elucidated by spectroscopic and chemical evidence. Complete 1H and 13C assignments were achieved by 2D NMR spectroscopy. The new compound showed weak activity against aldose reductase. It did not display antitumor activity against P-388 lymphoid neoplasm, A-549 human lung carcinoma, HT-29 human colon carcinoma, or MEL-28 human melanoma cell lines.

Original languageEnglish
Pages (from-to)82-85
Number of pages4
JournalJournal of Natural Products
Volume61
Issue number1
DOIs
StatePublished - 1998
Externally publishedYes

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