Friedelane triterpenoids from Maytenus macrocarpa

H. Chavez; A. Estevez-Braun; A. G. Ravelo; A. G. Gonzalez

doi:10.1021/np970232k

Friedelane triterpenoids from Maytenus macrocarpa

H. Chavez, A. Estevez-Braun, A. G. Ravelo, A. G. Gonzalez

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa. It includes a new friedelan triterpene (1), together with the known compounds friedelin, 3-oxo-29-hydroxyfriedelane, 3- oxofriedelan-25-al, and canophyllol. The structures of these compounds were elucidated by spectroscopic and chemical evidence. Complete ¹H and ¹³C assignments were achieved by 2D NMR spectroscopy. The new compound showed weak activity against aldose reductase. It did not display antitumor activity against P-388 lymphoid neoplasm, A-549 human lung carcinoma, HT-29 human colon carcinoma, or MEL-28 human melanoma cell lines.

Original language	English
Pages (from-to)	82-85
Number of pages	4
Journal	Journal of Natural Products
Volume	61
Issue number	1
DOIs	https://doi.org/10.1021/np970232k
State	Published - 1998
Externally published	Yes

Access to Document

10.1021/np970232k

Cite this

@article{f28203d8fe074d139998c7be0b5c7b34,

title = "Friedelane triterpenoids from Maytenus macrocarpa",

abstract = "A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa. It includes a new friedelan triterpene (1), together with the known compounds friedelin, 3-oxo-29-hydroxyfriedelane, 3- oxofriedelan-25-al, and canophyllol. The structures of these compounds were elucidated by spectroscopic and chemical evidence. Complete 1H and 13C assignments were achieved by 2D NMR spectroscopy. The new compound showed weak activity against aldose reductase. It did not display antitumor activity against P-388 lymphoid neoplasm, A-549 human lung carcinoma, HT-29 human colon carcinoma, or MEL-28 human melanoma cell lines.",

author = "H. Chavez and A. Estevez-Braun and Ravelo, {A. G.} and Gonzalez, {A. G.}",

year = "1998",

doi = "10.1021/np970232k",

language = "Ingl{\'e}s",

volume = "61",

pages = "82--85",

journal = "Journal of Natural Products",

issn = "0163-3864",

publisher = "American Chemical Society",

number = "1",

}

TY - JOUR

T1 - Friedelane triterpenoids from Maytenus macrocarpa

AU - Chavez, H.

AU - Estevez-Braun, A.

AU - Ravelo, A. G.

AU - Gonzalez, A. G.

PY - 1998

Y1 - 1998

N2 - A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa. It includes a new friedelan triterpene (1), together with the known compounds friedelin, 3-oxo-29-hydroxyfriedelane, 3- oxofriedelan-25-al, and canophyllol. The structures of these compounds were elucidated by spectroscopic and chemical evidence. Complete 1H and 13C assignments were achieved by 2D NMR spectroscopy. The new compound showed weak activity against aldose reductase. It did not display antitumor activity against P-388 lymphoid neoplasm, A-549 human lung carcinoma, HT-29 human colon carcinoma, or MEL-28 human melanoma cell lines.

AB - A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa. It includes a new friedelan triterpene (1), together with the known compounds friedelin, 3-oxo-29-hydroxyfriedelane, 3- oxofriedelan-25-al, and canophyllol. The structures of these compounds were elucidated by spectroscopic and chemical evidence. Complete 1H and 13C assignments were achieved by 2D NMR spectroscopy. The new compound showed weak activity against aldose reductase. It did not display antitumor activity against P-388 lymphoid neoplasm, A-549 human lung carcinoma, HT-29 human colon carcinoma, or MEL-28 human melanoma cell lines.

UR - http://www.scopus.com/inward/record.url?scp=0031932829&partnerID=8YFLogxK

U2 - 10.1021/np970232k

DO - 10.1021/np970232k

M3 - Artículo

C2 - 9461656

AN - SCOPUS:0031932829

SN - 0163-3864

VL - 61

SP - 82

EP - 85

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 1

ER -

Friedelane triterpenoids from Maytenus macrocarpa

Abstract

Access to Document

Fingerprint

Cite this