Cytotoxic triterpenoids from Maytenus retusa

Sandra M. Oramas-Royo, Haydee Chávez, Patricia Martín-Rodríguez, Leandro Fernández-Pérez, Ángel G. Ravelo, Ana Estévez-Braun

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by 1D and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC50 values ranging between 0.2 and 4.7 μM.

Original languageEnglish
Pages (from-to)2029-2034
Number of pages6
JournalJournal of Natural Products
Volume73
Issue number12
DOIs
StatePublished - 27 Dec 2010

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