The present study was designed to assess the relationship between adolescent loneliness and the following factors commonly associated with adult loneliness: attributional style, self-esteem, social anxiety, and social skills. Subjects were 186 ninth-grade students (107 males and 79 females) who were asked to complete seven different paper-and-pencil measures. Data were analyzed by calculating separate stepwise multiple regression equations for the total sample, males and females. Three significant predictors were found for the total sample: student social skills rating scale, self-esteem, and the perception of stability in interpersonal situations (attributional style). A different pattern of predictors emerged for males and females. Loneliness could be predicted for males from three variables: low self-esteem, the perception of uncontrollability in noninterpersonal situations, and self-perceptions of poor social skills. The best multiple predictors of loneliness for the females were self-perceptions of poor social skills, high social anxiety, and stable attributions for interpersonal situations.