An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation

Sandra Jiménez-Alonso; Haydee Chávez; Ana Estévez-Braun; Ángel G. Ravelo; Gabriela Feresin; Alejandro Tapia

doi:10.1016/j.tet.2008.06.057

An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation

Sandra Jiménez-Alonso
, Haydee Chávez
, Ana Estévez-Braun
, Ángel G. Ravelo
, Gabriela Feresin
, Alejandro Tapia

University of La Laguna
Hospital Universitario Nuestra Senora de Candelaria
Universidad Nacional de San Juan

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

The synthesis of novel pyrano embelin derivatives has been achieved through domino Knoevenagel hetero Diels-Alder reactions of embelin (1) with paraformaldehyde and electron rich alkenes. This synthetic approach is highly efficient when microwave irradiation is used.

Original language	English
Pages (from-to)	8938-8942
Number of pages	5
Journal	Tetrahedron
Volume	64
Issue number	37
DOIs	https://doi.org/10.1016/j.tet.2008.06.057
State	Published - 8 Sep 2008

Keywords

Knoevenagel heteroDiels-Alderreactions
MW irradiation
Multicomponent reactions
Quinones

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10.1016/j.tet.2008.06.057

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title = "An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation",

abstract = "The synthesis of novel pyrano embelin derivatives has been achieved through domino Knoevenagel hetero Diels-Alder reactions of embelin (1) with paraformaldehyde and electron rich alkenes. This synthetic approach is highly efficient when microwave irradiation is used.",

keywords = "Knoevenagel heteroDiels-Alderreactions, MW irradiation, Multicomponent reactions, Quinones",

author = "Sandra Jim{\'e}nez-Alonso and Haydee Ch{\'a}vez and Ana Est{\'e}vez-Braun and Ravelo, \{{\'A}ngel G.\} and Gabriela Feresin and Alejandro Tapia",

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T1 - An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation

AU - Jiménez-Alonso, Sandra

AU - Chávez, Haydee

AU - Estévez-Braun, Ana

AU - Ravelo, Ángel G.

AU - Feresin, Gabriela

AU - Tapia, Alejandro

PY - 2008/9/8

Y1 - 2008/9/8

N2 - The synthesis of novel pyrano embelin derivatives has been achieved through domino Knoevenagel hetero Diels-Alder reactions of embelin (1) with paraformaldehyde and electron rich alkenes. This synthetic approach is highly efficient when microwave irradiation is used.

AB - The synthesis of novel pyrano embelin derivatives has been achieved through domino Knoevenagel hetero Diels-Alder reactions of embelin (1) with paraformaldehyde and electron rich alkenes. This synthetic approach is highly efficient when microwave irradiation is used.

KW - Knoevenagel heteroDiels-Alderreactions

KW - MW irradiation

KW - Multicomponent reactions

KW - Quinones

UR - https://www.scopus.com/pages/publications/48049104329

U2 - 10.1016/j.tet.2008.06.057

DO - 10.1016/j.tet.2008.06.057

M3 - Artículo

AN - SCOPUS:48049104329

SN - 0040-4020

VL - 64

SP - 8938

EP - 8942

JO - Tetrahedron

JF - Tetrahedron

IS - 37

ER -

An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation

Abstract

Keywords

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